Ivermectin Does Not Alleviate Mild nature article ivermectin Covid
Ivermectin Does Not Alleviate Mild nature article ivermectin Covid
But the drug has also proved divisive. While some scientists see potential, others suspect that effectively inhibiting the coronavirus may require extremely high, potentially unsafe doses. Health officials have also worried that people desperate for coronavirus treatments might take versions of the drug that have been formulated for pets. “There’s been a lot of conflicting views on this, sometimes extreme conflicting views,” said Dr. Carlos Chaccour, a researcher at the Barcelona Institute for Global Health who was not involved in the new study. “I think it has become another hydroxychloroquine.” “There was a small signal there, and it would be interesting to see if that signal that we saw is real or not,” said Dr. López-Medina. “But that would have to be answered in a larger trial.” But she noted that the trial was relatively small and did not answer the most pressing clinical question, whether ivermectin can prevent severe disease or death. “Duration of symptoms may not be the most important either clinical or public health parameter to look at,” she said. But neither the proponents nor the critics have had much rigorous data to support their views. There are few well-controlled trials of the drug’s effectiveness against Covid-19, although more are expected in the coming months. And treatment guidelines from the National Institutes of Health note that there is not enough evidence “to recommend either for or against” using the drug in Covid-19 patients. The researchers did find that seven patients in the placebo group deteriorated after enrolling in the trial, compared to four in the ivermectin group, but the numbers were too small to draw a meaningful conclusion. Skip to content Skip to site index Science Today’s Paper Science | Popular Drug Does Not Alleviate Mild Covid-19 Symptoms, Study Finds s.com/2021/03/04/science/coronavirus-ivermectin-treatment.html Advertisement In the new study, Dr. López-Medina and his colleagues randomly assigned more than 400 people who had recently developed mild Covid-19 symptoms to receive a five-day course of either ivermectin or a placebo. They found that Covid-19 symptoms lasted about 10 days, on average, nature article ivermectin among people who received the drug, compared with 12 days among those who received the placebo, a statistically insignificant difference. “Ivermectin is currently being used widely,” said Dr. Eduardo López-Medina, a doctor and researcher at the Center for Pediatric Infectious Diseases in Cali, Colombia, who led the new trial. “In many countries in the Americas and other parts of the world, it’s part of the national guidelines of treating Covid.” Ivermectin Does Not Alleviate Mild nature article ivermectin CovidIvermectin Does Not Alleviate Mild nature article ivermectin Covid Such findings had spurred use of the drug against Covid-19, especially in Latin America . The new trial adds much-needed clinical data to the debate over using the drug to treat Covid-19, said Dr. Regina Rabinovich, a global health researcher at Harvard’s T.H. Chan School of Public Health, who was not involved in the study. Ivermectin, a drug typically used to treat parasitic worms, has been prescribed widely during the coronavirus pandemic, but rigorous data has been lacking. Ivermectin is typically used to treat parasitic worms in both people and animals, but scientific evidence for its efficacy against the coronavirus is thin. Some studies have indicated that the drug can prevent several different viruses from replicating in cells. And last year, researchers in Australia found that high doses of ivermectin suppressed SARS-CoV-2, the virus that causes Covid-19, in cell cultures. Dr. López-Medina also pointed out that the study population was relatively young and healthy, with an average age of 37 and few of the underlying conditions that can make Covid-19 more dangerous.
Ivermectin does not speed recovery in people with mild cases of Covid-19, according to a randomized controlled trial published in the journal JAMA today. Credit... Luis Robayo/Agence France-Presse — Getty Images By Emily Anthes Bigger trials, which are currently underway, could provide more definitive answers, said Dr. nature article natural immunity